High dose therapy for acute myelocytic leukemia treatment strategy: What is the choice?
نویسندگان
چکیده
منابع مشابه
New Developments in the Therapy of Acute Myelocytic Leukemia.
Current conventional treatment for patients with acute myelogenous leukemia results in a high percentage of clinical responses in most patients. However, a high percentage of patients still remain refractory to primary therapy or relapse later. This review examines the search for new agents and new modes of therapy. In Section I, Dr. Estey discusses new agents directed at various targets, such ...
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Since 1980, adults with acute myelocytic leukemia (AML) have been treated on two clinical studies using intensive timed sequential therapy. All patients ages 16 to 80, including those with secondary AML (SAML) and those with AML preceded by a hematologic disorder (AHD), were treated, regardless of medical complications at the time of diagnosis. The first study combined high doses of cytarabine ...
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given preliminary evidence of timed, sequential chemotherapy of high dose cytosine arabinoside the current study was initiated to assess the side effects and efficacy of this regimen in patients with newly acute myelocytic leukemia (aml). nineteen adults who referred to hematology-oncology and bone marrow transplantation (bmt) research center of tehran university of medical sciences were enroll...
متن کاملWhat is the optimal treatment for biphenotypic acute leukemia?
were: infection 9 (14%), accident 6 (9%), other 6 (9%), not known 5 (8%), malignancy 4 (6%), liver disease 3 (5%). Within the Birth Cohort, 18 (6%) patients died, 7 from cardiac causes. Three-hundred and four (55.9%) patients switched to CCT and 269 (49.4%) continued for at least six months. Indications for switching were: high serum ferritin (66.6%), deteriorating left ventricular function on ...
متن کاملMonitoring and treatment of acute kidney injury in children with acute lymphoblastic leukemia after high dose methotrexate chemotherapy
Abstact：objective To investigate acute kidney injury (AKI) in children with acute lymphoblastic leukemia (ALL) who received high dose methotrexate (MTX) chemotherapy and explore the corresponding treatment. Methods 180 children who received high dose MTX chemotherapy were observed with serum MTX concentration and serum creatinine. Patients with AKI of stage 3 or poor response to conventional tr...
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ژورنال
عنوان ژورنال: Annals of Oncology
سال: 1993
ISSN: 0923-7534
DOI: 10.1093/annonc/4.suppl_1.s59